Multiple antibiotic resistance (MAR) index and its reversion in Pseudomonas aeruginosa
نویسندگان
چکیده
منابع مشابه
Antibiotic resistance profiles of Pseudomonas aeruginosa isolates containing virulence genes
Background: A most common opportunistic pathogen, Pseudomonas aeruginosa is present in both humans and animals and responsible for various nosocomial infections and healthcare settings related infections. Different virulence genes like; oprL (membrane lipoprotein L) and toxA (exotoxin A i.e. ETA) in P. aeruginosa, assist in its pathogenicity, toxicity and contribute to high antibiotic resistanc...
متن کاملMechanisms of antibiotic resistance in Pseudomonas aeruginosa.
Pseudomonas aeruginosa is a notoriously difficult organism to control with antibiotics or disinfectants1. Recent reports on the antibiotic sensitivity patterns of P. aeruginosa in the UK have highlighted the problem of antibiotic resistance in cystic fibrosis (CF) strains in comparison with other hospital isolates2,3. Table 1 summarizes the current position in which the resistance rates of P. a...
متن کاملOuter Membrane Protein D Gene in Clinical Isolates of Pseudomonas Aeruginosa and its Role in Antibiotic Resistance
Background & Objectives: Pseudomonas aeruginosa is a common cause of nosocomial infection. OprD protein is a specific protein regulating the uptake of carbapenem antibiotic. Loss of OprD is the main mechanism of Pseudomonas Aeruginosa resistance to carbapenem. In this study, the presence of OprD gene is investigated in isolated Pseudomonas Aeruginosa in burn patients of Ghotboddin hospital in S...
متن کاملDevelopment of multiple-antibiotic-resistant (Mar) mutants of Pseudomonas aeruginosa after serial exposure to fluoroquinolones.
Laboratory-derived fluoroquinolone-resistant mutants were created by serially passaging wild-type Pseudomonas aeruginosa on fluoroquinolone-containing agar to obtain high-level fluoroquinolone resistance (e.g., ciprofloxacin MIC of 1,024 micrograms/ml). With increases of 4- to 32-fold in MICs of fluoroquinolones, these organisms demonstrated (relative to wild-type) normal morphology, resistance...
متن کاملCorrigendum: Evolved resistance to colistin and its loss due to genetic reversion in Pseudomonas aeruginosa
The increased reliance on colistin for treating multidrug-resistant Gram-negative bacterial infections has resulted in the emergence of colistin-resistant Pseudomonas aeruginosa. We attempted to identify genetic contributors to colistin resistance in vitro evolved isogenic colistin-resistant and -susceptible strains of two P. aeruginosa lineages (P5 and P155). Their evolutionary paths to acquis...
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ژورنال
عنوان ژورنال: Letters in Applied Microbiology
سال: 1997
ISSN: 0266-8254,1472-765X
DOI: 10.1046/j.1472-765x.1997.00364.x